[ACS] Discovery of NovelN-Linked Camptothecin Linker-Payloads to Access Antibody每Drug Conjugates with High Target-Mediated In Vivo Efficacy

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journalㄩJournal of Medicinal Chemistry

AuthorsㄩVlad Bacauanu; Si-Jie Chen; Simon B. Lang; Christian L. Morales; Nancy Zepeda; Manoj Charati; John A. Flygare; Rebecca E. Johnson; Ryan V. Quiroz; Song Yang; Olivia R. Chastain; Zhong L. Hua; Edward P. Bowman; Bernhard H. Geierstanger; Daniela M. Tomazela; Esther Kofman; Alycia K. Uyeoka; Fan Zhang; Laurence Fayadat-Dilman; Mengxuan Jia; Michael Judo; Ian Knemeyer; Peyman Akbari; Qingyun Yan; Evan R. Barry; Alan B. Northrup; W. Michael Seganish

Published dateㄩ--

DOIㄩ10.1021/acs.jmedchem.5c03693

PDF linkㄩhttps://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.5c03693

Article linkㄩhttps://doi.org/10.1021/acs.jmedchem.5c03693

Article SourceㄩAmerican Chemical Society (ACS)


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Georgee Post time 2026-5-7 13:06:41 | Show all posts

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