Development of Potent Mcl-1 Inhibitors: Structural Investigations on Macrocycles Originating from a DNA-Encoded Chemical Library Screen

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journal：Journal of Medicinal Chemistry

Authors：Koen F. W. Hekking; Sergio Maroto; Kees van Kekem; Frank S. Haasjes; Jack C. Slootweg; Patrick G. B. Oude Alink; Ron Dirks; Malvika Sardana; Marjon G. Bolster; Brian Kuijpers; Dennis Smith; Robin Doodeman; Marcel Scheepstra; Birgit Zech; Mark Mulvihill; Louis M. Renzetti; Lee Babiss; Paolo A. Centrella; Matthew A. Clark; John W. Cuozzo; Marie-Aude Guié; Eric Sigel; Sevan Habeshian; Christopher D. Hupp; Julie Liu; Heather A. Thomson; Ying Zhang; Anthony D. Keefe; Gerhard Müller; Stijn Gremmen

Published date：2024-2-22

DOI：10.1021/acs.jmedchem.3c02206

PDF link：https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.3c02206

Article link：https://doi.org/10.1021/acs.jmedchem.3c02206

Article Source：American Chemical Society (ACS)。

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[ACS] Development of Potent Mcl-1 Inhibitors: Structural Investigations on Macrocycles Originating from a DNA-Encoded Chemical Library Screen

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[ACS] Development of Potent Mcl-1 Inhibitors: Structural Investigations on Macrocycles Originating from a DNA-Encoded Chemical Library Screen Copy