The Discovery of Exarafenib (KIN-2787): Overcoming the Challenges of Pan-RAF Kinase Inhibition

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journal：Journal of Medicinal Chemistry

Authors：Young K. Chen; Toufike Kanouni; Lee D. Arnold; Jason M. Cox; Elisabeth Gardiner; Kathryn Grandinetti; Ping Jiang; Stephen W. Kaldor; Catherine Lee; Chun Li; Eric S. Martin; Nichol Miller; Eric A. Murphy; Noel Timple; John S. Tyhonas; Angie Vassar; Tim S. Wang; Richard Williams; Ding Yuan; Robert S. Kania

Published date：2024-2-8

DOI：10.1021/acs.jmedchem.3c01830

PDF link：https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.3c01830

Article link：https://doi.org/10.1021/acs.jmedchem.3c01830

Article Source：American Chemical Society (ACS)。

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[ACS] The Discovery of Exarafenib (KIN-2787): Overcoming the Challenges of Pan-RAF Kinase Inhibition

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[ACS] The Discovery of Exarafenib (KIN-2787): Overcoming the Challenges of Pan-RAF Kinase Inhibition