[ACS] Legumain-Cleavable Top1i Antibody-Drug Conjugates without Self-Immolative Spacers Demonstrate Potent Antitumor Activity

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journalㄩJournal of Medicinal Chemistry

AuthorsㄩVictor T. Ojo; Nicholas A. Bianchi; Michele Z. Yi; Samuel H. Chung; Meghan E. Gray; Mohammad Asikur Rahman; Kayla K. Elder; Tao Zhang; Tracy A. Brooks; L. Nathan Tumey

Published dateㄩ2025-12-11

DOIㄩ10.1021/acs.jmedchem.5c02681

PDF linkㄩhttps://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.5c02681

Article linkㄩhttps://doi.org/10.1021/acs.jmedchem.5c02681

Article SourceㄩAmerican Chemical Society (ACS)


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