Quinoxaline-based scaffolds as dual VEGFR-2/EGFR kinase inhibitors and apoptotic inducers: Design, synthesis, anticancer evaluation, and in silico study

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journal：Bioorganic Chemistry

Authors：Alaa Elwan; Samiha A. El-Sebaey; Hanan A. AL-Ghulikah; Reda R. Mabrouk; Abo bakr Zaki; Mohamed Abbas; Ismail Celik; Mohamed Ayman El-Zahabi; Abdallah E. Abdallah; Mona S. El-Zoghbi

Published date：2026-8-

DOI：10.1016/j.bioorg.2026.109918

PDF link：https://www.sciencedirect.com/sc ... 045206826004542/pdf

Article link：https://doi.org/10.1016/j.bioorg.2026.109918

Article Source：Elsevier BV。

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[Elsevier] Quinoxaline-based scaffolds as dual VEGFR-2/EGFR kinase inhibitors and apoptotic inducers: Design, synthesis, anticancer evaluation, and in silico study

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[Elsevier] Quinoxaline-based scaffolds as dual VEGFR-2/EGFR kinase inhibitors and apoptotic inducers: Design, synthesis, anticancer evaluation, and in silico study