Discovery of High-Affinity SMARCA2/4 Bromodomain Ligands and Development of Potent and Exceptionally Selective SMARCA2 PROTAC Degraders

Post time 7 day(s) ago

journal：Journal of Medicinal Chemistry

Authors：Lingying Leng; Wenbin Tu; Lin Yang; Liyue Huang; Mi Wang; Jennifer L. Meagher; Krishnapriya Chinnaswamy; Srinivasa Rao Allu; Rohan Kalyan Rej; Jelena Toovi; Lalgudi Harikrishnan; Zhenwu Li; Zhihua Sui; Jeanne A. Stuckey; Shaomeng Wang

Published date：2025-1-23

DOI：10.1021/acs.jmedchem.4c01903

PDF link：https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.4c01903

Article link：https://doi.org/10.1021/acs.jmedchem.4c01903

Article Source：American Chemical Society (ACS)。

Remark：

Post time 7 day(s) ago

: This post has been completed
Completed attachments will be deleted within 24 hours.

[ACS] Discovery of High-Affinity SMARCA2/4 Bromodomain Ligands and Development of Potent and Exceptionally Selective SMARCA2 PROTAC Degraders

Best Answer

Same Category

Latest Reply

Announcement

Daily Top Contributors

[ACS] Discovery of High-Affinity SMARCA2/4 Bromodomain Ligands and Development of Potent and Exceptionally Selective SMARCA2 PROTAC Degraders Copy

Best Answer

Same Category

Latest Reply

Announcement

Daily Top Contributors

[ACS] Discovery of High-Affinity SMARCA2/4 Bromodomain Ligands and Development of Potent and Exceptionally Selective SMARCA2 PROTAC Degraders