Structure and evolution-guided design of minimal RNA-guided nucleases

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journal：Science

Authors：Petr Skopintsev; Isabel Esain-Garcia; Evan C. DeTurk; Peter H. Yoon; Zehan Zhou; Trevor Weiss; Maris Kamalu; Ajit Chamraj; Kenneth J. Loi; Conner J. Langeberg; Ron S. Boger; Hunter Nisonoff; Hannah M. Karp; Lin-Xing Chen; Honglue Shi; Kamakshi Vohra; Jillian F. Banfield; Jamie H. D. Cate; Steven E. Jacobsen; Jennifer A. Doudna

Published date：2026-7-16

DOI：10.1126/science.aed6123

PDF link：https://www.science.org/doi/pdf/10.1126/science.aed6123

Article link：https://doi.org/10.1126/science.aed6123

Article Source：American Association for the Advancement of Science (AAAS)。

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