[Elsevier] Covalent JAK3 inhibitors based on 2-arylamino and 7H-pyrrolo[2,3-d]pyrimidine scaffold: design, synthesis, and biological evaluation for the potential treatment of bortezomib-resistant multiple myeloma

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journalㄩEuropean Journal of Medicinal Chemistry

AuthorsㄩLiangliang Tian; Jiaxun Li; Jiawen Yu; Qingxuan Han; Nafiseh Bolghanabadi; Ke Wang; Zhiping Chen; Xu Zheng; Peng Chu; Lixue Chen

Published dateㄩ2026-6-

DOIㄩ10.1016/j.ejmech.2026.118764

PDF linkㄩhttps://www.sciencedirect.com/sc ... 223523426002096/pdf

Article linkㄩhttps://doi.org/10.1016/j.ejmech.2026.118764

Article SourceㄩElsevier BV


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