[Nature] To TnpB or not TnpB? Cas12 is the answer

Shivamchauhan Post time Yesterday 12:45 | Show all posts |Read mode
This post will be closed automatically in 2026-07-28 12:42
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Investigation into the evolutionary history of class II CRISPR systems revealed that RNA-guided endonucleases Cas9 and Cas12 evolved from IscB and TnpB proteins, which possess surprisingly similar function to their Cas orthologs1,2,3. Kim et al. claim to have discovered
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