Reappraising Dichloromethane: Uncovering a Hidden Coupling Reagent for Activating Carboxylic Acids in Direct Amide Synthesis

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journal：Journal of the American Chemical Society

Authors：Nithin Pootheri; Abbas Haruna Umar; Sunwoo Lee

Published date：2026-7-15

DOI：10.1021/jacs.6c05971

PDF link：https://pubs.acs.org/doi/pdf/10.1021/jacs.6c05971

Article link：https://doi.org/10.1021/jacs.6c05971

Article Source：American Chemical Society (ACS)。

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[ACS] Reappraising Dichloromethane: Uncovering a Hidden Coupling Reagent for Activating Carboxylic Acids in Direct Amide Synthesis

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