Carboxamide-Bearing Panobinostat Analogues Designed To Interact with E103-D104 at the Cavity Opening of Class I HDAC Isoforms

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journal：ACS Medicinal Chemistry Letters

Authors：Callum A. Rosser; Samuel V. Feeney; Lukas Roth; David E. Hibbs; Michael P. Gotsbacher; Rachel Codd

Published date：2025-2-13

DOI：10.1021/acsmedchemlett.4c00494

PDF link：https://pubs.acs.org/doi/pdf/10.1021/acsmedchemlett.4c00494

Article link：https://doi.org/10.1021/acsmedchemlett.4c00494

Article Source：American Chemical Society (ACS)。

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[ACS] Carboxamide-Bearing Panobinostat Analogues Designed To Interact with E103-D104 at the Cavity Opening of Class I HDAC Isoforms

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[ACS] Carboxamide-Bearing Panobinostat Analogues Designed To Interact with E103-D104 at the Cavity Opening of Class I HDAC Isoforms