Costunolide ameliorates autoimmune uveitis by targeting USP15 to suppress TNF-α-induced retinal endothelial inflammation

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journal：Proceedings of the National Academy of Sciences

Authors：Yu Gao; Xingran Li; Lingyu Dai; Xiang Luo; Guannan Su; Kai Shi; Ling Chen; Peizeng Yang

Published date：2026-7-14

DOI：10.1073/pnas.2533845123

PDF link：https://pnas.org/doi/pdf/10.1073/pnas.2533845123

Article link：https://doi.org/10.1073/pnas.2533845123

Article Source：National Academy of Sciences。

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[Other] Costunolide ameliorates autoimmune uveitis by targeting USP15 to suppress TNF-α-induced retinal endothelial inflammation