Development of Scalable Processes for the Preparation of 4-(chloromethyl)-1-cyclohexyl-2-(trifluoromethyl)benzene: A Key Intermediate for Siponimod

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journal：Organic Process Research & Development

Authors：Biyue Lin; Shuming Wu; Qingbo Xiao; Jingping Kou; Ji’an Hu; Zhu Zhu; Xinglin Zhou; Jiang Weng; Zhongqing Wang

Published date：2023-8-18

DOI：10.1021/acs.oprd.3c00170

PDF link：https://pubs.acs.org/doi/pdf/10.1021/acs.oprd.3c00170

Article link：https://doi.org/10.1021/acs.oprd.3c00170

Article Source：American Chemical Society (ACS)。

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[ACS] Development of Scalable Processes for the Preparation of 4-(chloromethyl)-1-cyclohexyl-2-(trifluoromethyl)benzene: A Key Intermediate for Siponimod

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[ACS] Development of Scalable Processes for the Preparation of 4-(chloromethyl)-1-cyclohexyl-2-(trifluoromethyl)benzene: A Key Intermediate for Siponimod Copy

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[ACS] Development of Scalable Processes for the Preparation of 4-(chloromethyl)-1-cyclohexyl-2-(trifluoromethyl)benzene: A Key Intermediate for Siponimod