[ACS] Discovery of Novel Bicyclic Pyrazole Amides as Potent Neuronal KV7 Potassium Channel Openers with Strong Preclinical Antiseizure Activity.

varungerrard Post time The day before yesterday 19:15 | Show all posts |Read mode
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Edited by varungerrard at 2026-8-24 19:17

Discovery of Novel Bicyclic Pyrazole Amides as Potent Neuronal KV7 Potassium Channel Openers with Strong Preclinical Antiseizure Activity.
Shaoyi Sun, Qi Jia, Girish Bankar, Kristen N. Burford, Jessica Christabel, Helen A. Clement, Gina de Boer, Zirui Feng, Chido M. Hambira, Stephen K. Jackson, Kuldip Khakh, Rainbow Kwan, Stephanie Lee, Jenny Li, Andrea Lindgren, Janette Mezeyova, Juliette Sabbatini, Art Urrutia, Paul Charifson, Michael P. Clark, Steven S. Wesolowski, James P. Johnson, James R. Empfield, Christoph M. Dehnhardt, Richard Dean;
ACS Med. Chem. Lett. 2026;
https://doi.org/10.1021/acsmedchemlett.6c00360

https://pubs.acs.org/amclct/arti ... rectedFrom=fulltext

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