[Elsevier] Structure-guided expansion strategy unveils potent allosteric SHP2 inhibitors with synergistic efficacy against AML through MCL-1 co-targeting

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journalㄩEuropean Journal of Medicinal Chemistry

AuthorsㄩMaoqian Zhang; Shuyun Wu; Menghui Liu; Haozhe Li; Luyao Wang; Feimeng Duan; Rui Han; Chenxiao Shan; Zequn Jiang; Junzhuo Liao; Yongmin Zhang; Wei Li; Bo Wang

Published dateㄩ2025-11-

DOIㄩ10.1016/j.ejmech.2025.117988

PDF linkㄩhttps://www.sciencedirect.com/sc ... 223523425007536/pdf

Article linkㄩhttps://doi.org/10.1016/j.ejmech.2025.117988

Article SourceㄩElsevier BV


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