Antibodies against MLC1 found in patients with NMOSD-like disease mediate astrocytopathy in rodent models

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journal：Science Translational Medicine

Authors：Hoi Kiu Wong; Samantha Ho; Qian Yu; Katherine S. Given; Dorina Shqau; Selia Baier; Stephan Winklmeier; Heike Rübsamen; Arek Kendirli; Kathrin Schanda; Eva Oswald; Katharina Bruer; Franziska S. Thaler; Lisa Ann Gerdes; Regina Feederle; Martin Kerschensteiner; Markus Reindl; Mohsen Khademi; Fredrik Piehl; Tomas Olsson; Jeffrey L. Bennett; Tania Kümpfel; Naoto Kawakami; Monika Bradl; Edgar Meinl; Simone Mader

Published date：2026-8-26

DOI：10.1126/scitranslmed.ady0403

PDF link：https://www.science.org/doi/pdf/10.1126/scitranslmed.ady0403

Article link：https://doi.org/10.1126/scitranslmed.ady0403

Article Source：American Association for the Advancement of Science (AAAS)。

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[AAAS] Antibodies against MLC1 found in patients with NMOSD-like disease mediate astrocytopathy in rodent models

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[AAAS] Antibodies against MLC1 found in patients with NMOSD-like disease mediate astrocytopathy in rodent models