The brain-derived neurotrophic factor mimetic 7,8-dihydroxyflavone mitigates NLRP3 inflammasome activation and GSDMD-mediated pyroptosis and enhances the negative regulatory pathways of pyroptosis in microglia

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journal：Journal of Neuroimmunology

Authors：Mehmet Erdem; eniz Erdem; Süleyman Caner Karahan; Ahmet Alver; Soner Karabulut; Gkhan Yldz

Published date：2025-9-

DOI：10.1016/j.jneuroim.2025.578684

PDF link：https://www.sciencedirect.com/sc ... 165572825001651/pdf

Article link：https://doi.org/10.1016/j.jneuroim.2025.578684

Article Source：Elsevier BV。

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[Elsevier] The brain-derived neurotrophic factor mimetic 7,8-dihydroxyflavone mitigates NLRP3 inflammasome activation and GSDMD-mediated pyroptosis and enhances the negative regulatory pathways of pyroptosis in microglia

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[Elsevier] The brain-derived neurotrophic factor mimetic 7,8-dihydroxyflavone mitigates NLRP3 inflammasome activation and GSDMD-mediated pyroptosis and enhances the negative regulatory pathways of pyroptosis in microglia Copy

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[Elsevier] The brain-derived neurotrophic factor mimetic 7,8-dihydroxyflavone mitigates NLRP3 inflammasome activation and GSDMD-mediated pyroptosis and enhances the negative regulatory pathways of pyroptosis in microglia