[Other] Late-stage functionalization with strain-release warheads enables tunable covalent inhibition

Pashamk Post time 7 day(s) ago | Show all posts |Read mode
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journalㄩScience

AuthorsㄩZachary P. Shultz; Ansar Lee-Sam; Yun-Pu Chang; Luxin Sun; Dylan Grassie; Alessio Gabellini; Kyle Pedretty; Thomas Scattolin; Victoria Izumi; Bin Fang; Samer Sansil; Ramu Kakumanu; Lukasz Wojtas; John Koomen; Ernst Schnbrunn; Andrii Monastyrskyi; Derek Duckett; Justin M. Lopchuk

Published dateㄩ2026-7-23

DOIㄩ10.1126/science.adx7219

PDF linkㄩhttps://www.science.org/doi/pdf/10.1126/science.adx7219

Article linkㄩhttps://doi.org/10.1126/science.adx7219

Article SourceㄩAmerican Association for the Advancement of Science (AAAS)


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