Efficacy and safety evaluation of intense pulsed light therapy combined with salicylic acid in rosacea treatment

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S. Lan, P. Liang, Y. Tang, J. Song and Q. Liu

2024

Objective: To explore the efficacy and safety of intense pulsed light (IPL) therapy combined with supramolecular salicylic acid in rosacea treatment. Methods: A total of 40 patients with rosacea admit⁃ ted to Zhongnan Hospital of Wuhan University from April to October 2023 were enrolled as the study subjects, and were randomly divided into the study group (n=20), with IPL therapy combined with supramolecular salicylic acid treatment, and the control group (n=20), with IPL therapy alone. After 12 weeks of treatment, the total effective rate, facial erythema score, and the incidence of adverse re⁃ actions during treatment were evaluated in both groups. Results: The total effective rate of the control group was lower than that of the study group after 12 weeks of treatment (P<0. 05). After treatment, the facial erythema score in both groups decreased, and the study group showed lower values than the control group (P<0. 05). There was no significant difference in the incidence of adverse reactions be⁃ tween the two groups (P<0. 05). Conclusion: IPL ⁃ combined salicylic acid treatment of rosacea demonstrates superior clinical efficacy and a good safety profile. It can effectively promote the recovery of skin lesions, and reduce facial erythema. © 2024 Editorial Board of Medical Journal of Wuhan University. All rights reserved.

doi:10.14188/j.1671-8852.2024.0307

https://www.scopus.com/pages/publications/85211969484?origin=resultslist

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